Micotherapy Reishi

Lai CY, Hung JT, Lin HH, Alice LY, Chen SH, Tsai YC, Shao LE, Yang WB, Yu J. Immunomodulatory and adjuvant activities of a polysaccharide extract of Ganoderma lucidum in vivo and in vitro. Vaccine. 2010 Jul 12;28(31):4945-54.

Xu Z, Chen X, Zhong Z, Chen L, Wang Y. Ganoderma lucidum polysaccharides: immunomodulation and potential anti-tumor activities. The American journal of Chinese medicine. 2011;39(01):15-27.

Hu Z, Du R, Xiu L, Bian Z, Ma C, Sato N, Hattori M, Zhang H, Liang Y, Yu S, Wang X. Protective effect of triterpenes of Ganoderma lucidum on lipopolysaccharide-induced inflammatory responses and acute liver injury. Cytokine. 2020 Mar 1;127:154917.

Montalbano G. Evaluation of the antimicrobial, anti-inflammatory, regenerative and wound healing properties of the bracket fungus ganoderma lucidum (Doctoral dissertation, Queensland University of Technology).

Hsu PL, Lin YC, Ni H, Mo FE. Ganoderma triterpenoids exert antiatherogenic effects in mice by alleviating disturbed flow-induced oxidative stress and inflammation. Oxidative medicine and cellular longevity. 2018;2018.

Bhardwaj N, Katyal P, K Sharma A. Suppression of inflammatory and allergic responses by pharmacologically potent fungus Ganoderma lucidum. Recent patents on inflammation & allergy drug discovery. 2014 May 1;8(2):104-17.

Wang C, Shi S, Chen Q, Lin S, Wang R, Wang S, Chen C. Antitumor and immunomodulatory activities of Ganoderma lucidum polysaccharides in glioma-bearing rats. Integrative cancer therapies. 2018 Sep;17(3):674-83.

Wang G, Wang L, Zhou J, Xu X. The Possible Role of PD-1 Protein in Ganoderma lucidum–Mediated Immunomodulation and Cancer Treatment. Integrative cancer therapies. 2019 Oct;18:1534735419880275.

Jin X, Beguerie JR, Sze DM, Chan GC. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane Database of Systematic Reviews. 2012(6).

Barbieri A, Quagliariello V, Del Vecchio V, Falco M, Luciano A, Amruthraj NJ, Nasti G, Ottaiano A, Berretta M, Iaffaioli RV, Arra C. Anticancer and anti-inflammatory properties of Ganoderma lucidum extract effects on melanoma and triple-negative breast cancer treatment. Nutrients. 2017 Mar;9(3):210.

Cao Y, Xu X, Liu S, Huang L, Gu J. Ganoderma: A cancer immunotherapy review. Frontiers in pharmacology. 2018 Oct 25;9:1217.

Petrova, Roumyana D., et al. “Fungal metabolites modulating NF-κB activity: an approach to cancer therapy and chemoprevention.” Oncology Reports 19.2 (2008): 299-308.

Hasnat, Md Abul, et al. “Anti-inflammatory activity on mice of extract of Ganoderma lucidum grown on rice via modulation of MAPK and NF-kB pathways.” Phytochemistry 114 (2015): 125-136.

Yoon, Hyun-Min, et al. “Ganoderma lucidum ethanol extract inhibits the inflammatory response by suppressing the NF-kB and toll-like receptor pathways in lipopolysaccharide-stimulated BV2 microglial cells.” Experimental and therapeutic medicine 5.3 (2013): 957-963.

Dudhgaonkar, Shailesh, Anita Thyagarajan, and Daniel Sliva. “Suppression of the inflammatory response by triterpenes isolated from the mushroom Ganoderma lucidum.” International immunopharmacology 9.11 (2009): 1272-1280.

Chang CJ, Lin CS, Lu CC, et al. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota. Nature communications. 2015 Jun 23;6(1):1-9.

Delzenne NM, Bindels LB. Ganoderma lucidum, a new prebiotic agent to treat obesity?. Nature Reviews Gastroenterology & Hepatology. 2015 Oct;12(10):553-4.

Chang CJ, Lin CS, Lu CC, et al. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota. Nature communications. 2015 Jun 23;6(1):1-9.

Jin M, Zhu Y, Shao D, et al. Effects of polysaccharide from mycelia of Ganoderma lucidum on intestinal barrier functions of rats. International journal of biological macromolecules. 2017 Jan 1;94:1-9.

Chang CJ, Lin CS, Lu CC, et al. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota. Nature communications. 2015 Jun 23;6(1):1-9.

Xu S, Dou Y, Ye B, et al. Ganoderma lucidum polysaccharides improve insulin sensitivity by regulating inflammatory cytokines and gut microbiota composition in mice. Journal of Functional Foods. 2017 Nov 1;38:545-52.

Chang CJ, Lin CS, Lu CC, et al. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota. Nature communications. 2015 Jun 23;6(1):1-9.

Chang CJ, Lin CS, Lu CC, et al. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota. Nature communications. 2015 Jun 23;6(1):1-9.

Hu R, Guo W, Huang Z, Li L, Liu B, Lv X. Extracts of Ganoderma lucidum attenuate lipid metabolism and modulate gut microbiota in high-fat diet fed rats. Journal of Functional Foods. 2018 Jul 1;46:403-12.

Guo WL, Pan YY, Li L, et al. Ethanol extract of Ganoderma lucidum ameliorates lipid metabolic disorders and modulates the gut microbiota composition in high-fat diet fed rats. Food & function. 2018;9(6):3419-31.

Chang CJ, Lin CS, Lu CC, et al. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota. Nature communications. 2015 Jun 23;6(1):1-9.

Wu Q, Zhang H, Wang PG, Chen M. Evaluation of the efficacy and safety of Ganoderma lucidum mycelium-fermented liquid on gut microbiota and its impact on cardiovascular risk factors in human. Rsc Advances. 2017;7(71):45093-100.

Xu S, Dou Y, Ye B, et al. Ganoderma lucidum polysaccharides improve insulin sensitivity by regulating inflammatory cytokines and gut microbiota composition in mice. Journal of Functional Foods. 2017 Nov 1;38:545-52.

Holmes D. Medicinal mushroom reduces obesity by modulating microbiota. Nature Reviews Endocrinology. 2015 Sep;11(9):504-.

Kubota A, Kobayashi M, Sarashina S, et al. Reishi mushroom Ganoderma lucidum Modulates IgA production and alpha-defensin expression in the rat small intestine. Journal of ethnopharmacology. 2018 Mar 25;214:240-3.

Tran HB, Yamamoto A, Matsumoto S, et al. Hypotensive effects and angiotensin-converting enzyme inhibitory peptides of reishi (Ganoderma lingzhi) auto-digested extract. Molecules. 2014 Sep;19(9):13473-85.

Lee SY, Rhee HM. Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action. Chemical and Pharmaceutical Bulletin. 1990 May 25;38(5):1359-64.

Shevelev OB, Seryapina AA, Zavjalov EL, et al. Hypotensive and neurometabolic effects of intragastric Reishi (Ganoderma lucidum) administration in hypertensive ISIAH rat strain. Phytomedicine. 2018 Mar 1;41:1-6.

Gao Y, Chen G, Dai X, Ye J, Zhou S. A phase I/II study of ling zhi mushroom Ganoderma lucidum (W. Curt.: Fr.) Lloyd (Aphyllophoromycetideae) extract in patients with coronary heart disease. International Journal of Medicinal Mushrooms. 2004;6(4).

Sudheesh NP, Ajith TA, Janardhanan KK. Ganoderma lucidum (Fr.) P. Karst enhances activities of heart mitochondrial enzymes and respiratory chain complexes in the aged rat. Biogerontology. 2009 Oct 1;10(5):627-36.

Liyun WF. Preventive effect of Ganoderma lucidum polysaccharides on formation of atherosclerosis in experimental rats [J]. Journal of Nantong University (Medical Sciences). 2008;4.

Hsu PL, Lin YC, Ni H, Mo FE. Ganoderma triterpenoids exert antiatherogenic effects in mice by alleviating disturbed flow-induced oxidative stress and inflammation. Oxidative medicine and cellular longevity. 2018;2018.

Sargowo D, Ovianti N, Susilowati E, Ubaidillah N, Nugraha AW, Proboretno KS, Failasufi M, Ramadhan F, Wulandari H, Waranugraha Y, Putri DH. The role of polysaccharide peptide of Ganoderma lucidum as a potent antioxidant against atherosclerosis in high risk and stable angina patients. Indian heart journal. 2018 Sep 1;70(5):608-14.

Kwok Y, Ng KF, Li CC, Lam CC, Man RY. A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesthesia & Analgesia. 2005 Aug 1;101(2):423-6